What is Andarine?
S4 Andarine is currently being sold as a Selective Androgen Receptor Modulator (SARM) but what you don’t know is that it started out as a male contraceptive. Yes, the idea behind this product was for family planning purposes where it had already managed to reduce spermatogenesis successfully. This explains the dozens of cases of men out there that were using this compound and had a tough time getting their wives pregnant.
It was not until a certain clinical trial was done on mice where scientists noticed S4’s ability to increase muscle mass and bone density. They realized how incredibly selective the tissue growth influenced by this compound is and that’s when the idea of using S4 Andarine for muscle growth came up. This raised interests for further studies, which have provided even more information that helps us understand more about Andarine and how it works.
How S4 Andarine Works
Three chemicals influence the performance of Androgen Receptors which include:
- AR Antagonist – This chemical attaches itself to the receptor, and once this happens the receptor can no longer be activated.
- AR Agonist – Unlike the androgen receptor antagonist that only binds once, the agonist will attach to the receptor and then detach itself before attaching again. Agonist chemicals behave like this over and over.
- AR Modulator – These chemicals uniquely affect receptor, and this is where the S4 Andarine falls. AR Modulators bind to the receptors and then go further to change its structure making the receptors to function as instructed by the modulator.
What happens, therefore, is that once S4 or any other effective SARM compound gets into your system, it binds to your Androgen Receptors and sticks on it. When receptors come into contact with testosterone the S4 influences the receptors to make genes that are only beneficial in bone and muscle growth. In simpler words, S4 Androgen works similarly as steroids except its anabolic activities are much safer and hence do not result in all those adverse effects prevalent in steroid users.
Benefits of using S4 Andarine
The best part about using this compound is that there is so much information around which helps you to know what you can expect from it. S4 is widely researched, in fact, it was the first ever SARM compound that was approved for a second stage clinical trial. We can hence, confidently say that it is the most analyzed SARM out there whose anabolic efficacy is undebatable. Scientists have verified its benefits and recommend its use as an alternative treatment for osteoporosis, muscle wasting, some renal diseases, and other hypogonadism problems.
- Muscle Improvement
The most significant benefit of S4 Andarine is, without doubt, its preservation and improvement of lean muscle mass. The compound is exceptional for this purpose. The first clinical trial on S4 showed that its consumption could result in a 3.3 lbs increase in muscles within 90 days and guess what, this was achieved without a change in diet or increase in any exercises!
- Muscle Regeneration
The first clinical study was done on this SARM also involved volunteers with degenerative disorders. They were all placed under a daily dosage of at least 3mg/kg. After 1-2 weeks the study noticed a significant boost in muscle regeneration and the patients didn’t even have to take part in any exercises. The study, however, also noticed a few side effects in some of these patients and they were all attributed to the dosages used. To avoid these effects, it was therefore recommended that you be extra keen on daily dosages of S-4 to prevent adverse reactions.
- Reduction in Muscle Fat
Imagine using a SARM whose side effect is a reduction in body fat! This is precisely what S4 does. While your body is experiencing insane muscle mass growth, you will, on the other hand, be enjoying a decrease in body fat which allows you to gain muscles even faster. A decrease in body fat is, however, a subjective matter. People with specific genes may be unable to experience this change. The good news is that everyone should be able to enjoy the S4’s ability in oxidizing fatty tissues.
- S4 causes minimal growth in sexual organs like prostate
- Chances of getting cardiovascular diseases are much lower when compared to users of other steroids. This is because S4 does not affect the LDL/HDL ratio
- Unlike typical steroids, SARMs such as S-4 expose you to fewer risks of getting hepatitis and hepatotoxicity because they don’t need any liver enzymes for anabolic effects to be activated.
- Testosterone levels are not affected
- It’s highly selective, and hence other vital organs like the heart won’t be affected
- Zero chances of getting female characteristics such as breast enlargement
- S-4 is not as powerful as steroids, but the good thing is that using these SARMs you won’t need the exhausting post cycle therapy that’s necessary when using steroids. S-4 can be cycled throughout the year helping you to experience almost similar results.
- Women can also enjoy the vast benefits of S-4 without having to deal with masculine features.
Side Effects of Using S-4
S4 just like many other SARMs comes with its side effects. It is, fortunately, described as a ligand which means that even if you use it at extremely high levels, you may experience a few side effects, but none of them will leave permanent damage on you.
The most prevalent side effects are perhaps related to visual problems. A lot of S-4 users expressed their concerns in adjusting to night vision. If you are one of the people with this problem stop using the drug daily and instead take the SARM for five days and then take a break of 2 days. This should help you reduce the visual effects. Once you stop using S4 entirely your night vision issues will also disappear.
Most SARMs have also been linked with psychological effects in some people. Consumption of S-4 could, therefore, cause depression. It’s advisable that if you notice you are experiencing this problem you seek for physician’s help right away to forge a new way forward.
Finally, you should know that continuous usage of S-4 can generate tolerance of the compound in your system. At some point, you may hence start noticing that you are not enjoying as many benefits as you were a few weeks back. This can be solved by increasing the dosage (if your body is tolerant enough) or taking a break for some time before restarting the cycle again.
The recommended dosages of Andarine hugely depend on the results you are looking for:
For Reducing Body Fat
S-4 delivers incredible fat burning benefits. Its usage will reduce the effects of Lipoprotein Lipase (LPL), the enzyme responsible for storage of fat in the body. It will also oxidize fat which will consequently be used as a source of energy.
For this purpose, the recommended dosage is 50 mg taken for 6-8 weeks cycles with a 2-day break in between.
For Muscle Bulking
S-4 isn’t exactly the best SARM for bulking. Several other SARMs are better formulated with more excellent results than S4 for this purpose. It can, however, still be used for bulking where you’ll witness reasonably larger muscle growths, and all this will be achieved while keeping you relatively lean.
To enjoy optimal muscle mass growth and a decrease in body fat you’ll need to take 50-75 mg of S4 for 4-8 weeks.
Where can I buy S4 Andarine?
The SARM is available on multiple online retail stores in both liquid and pill form. If you are looking for liquid Andarine, you can quickly get it from the official page of Proven Peptides. They have decent deals, and their products are of high quality.
S4 capsules are also available in Medfit’s Adonis and Jacked the Ripper websites.
S-4 is a fantastic SARM with significant benefits. Users have lost massive amounts of weight while gaining muscle mass without even having to intensify their workout sessions. Painful muscle pumps isn’t an issue using this supplement and the best part yet is that you won’t experience any of those embarrassing effects of breast enlargement or other female characteristics. The unique performance of Andarine gives it a cutting edge that makes it rise way above most other SARMs in the market, and that’s why it is recommended to bodybuilders and other athletes.
Jonathan Deventer is a passionate Certified Personal Trainer who got his Master’s Degree in Human Kinetics at the Boise State University.
He specializes in steroids, peptides, SARMS and pre-workout supplements.
- BCAK Certified Exercise Physiologist
- Certified Fitness Consultant
- Athletic Taping Level I & II BCRPA
- Personal Trainer, BCRPA
- Supervisor of Fitness Leaders