What is Ligandrol (LGD 4033)?
Ligandrol or LGD 4033 is a very popular Selective Androgen Receptor Modulator. LGD 4033 is the strongest non-steroidal SARM consumed orally. This compound is not just useful to athletes due to its compelling nature but is also a favorite because of its exceptional bioavailability. Users of Ligandrol will see results much faster because the compound is quickly absorbed into one’s system moving to all the necessary remote locations in the body.
Ligandrol is currently the best supplement usable to any athlete looking to reduce body fat, boost lean muscle mass and to recomp. Medically, studies are underway to investigate the compound’s ability to treat age-related muscle loss, muscle wasting due to acute or chronic diseases, cancer and osteoporosis.
Who Makes Ligandrol?
The Ligand Pharmaceuticals initially discovered Ligandrol, but its potency raised interests in the industry which saw other companies initiate their own trials. Currently, it is being developed as VK5211 by the Vikings Therapeutics.
How Does it Work?
Like many other SARMs, Ligandrol binds to the androgen receptors activating them to enhance anabolic activities which selectively affects bones and muscles. It thereby helps to promote the growth of muscle mass and bone density delivering results almost similar to ones from steroids except it doesn’t have any adverse effects.
Ligandrol has been subjected to two distinct studies all of which were aimed at understanding the link between this compound and bone and muscle growth.
The first trial phase investigated the effects of Ligandrol on muscle strength and lean body mass. This study involved 76 healthy male subjects that were supplemented with 0.1mg, 0.3mg or 1mg of Ligandrol for 21 days. At the end of this period, the effects of Ligandrol were observed through muscle strength, change in lean body mass, sex hormones, and stair-climbing power. The outcomes were astonishing because the compound not only showed its capability to improve lean body mass and strength, but it did so with zero cases of adverse effects being reported!
The second ongoing clinical phase of Ligandrol is spearhead by the Vikings Pharmaceuticals. This phase is more interested in establishing the potential benefits of LGD 4033 in patients that have undergone hip fracture surgery.
Ligandrol’s ability to boost bone mineral density is one of the reasons behind this study. If the compound is active enough to improve bone density, then chances of it helping individuals recovering from hip fractures are very high, and that’s what the study seeks to prove. This SARM could, therefore, be an ideal choice for the elderly where falls and hip fractures are more prevalent.
Benefits of Using Ligandrol
Ligandrol users are guaranteed seven key benefits. These are not theoretical benefits, but they are also adequately backed by clinical trials and real user’s testimonials. They include:
- Increase in Lean Muscle Mass
This is the primary benefit of taking Ligandrol which every user can testify about. LGD 4033 will increase your muscle mass while keeping fat levels low. In the first phase of clinical trials, it was established that taking 1mg of LGD 4033 for 21 days will result in a gain of around 2.66 lbs lean body mass. The study explained that this benefit is dose-dependent and hence if you want to see a more significant impact all you need is to increase the dosage safely.
- Enhances strength and stamina
At the end of the 21-day study, Stair-climbing power had increased dramatically in all the subjects especially the ones who had received higher dosages of Ligandrol. The users were also able to withstand more physical activities that were initially problematic to undertake. Going through various user reviews online you will also see testimonies on how taking Ligandrol has helped increase endurance among cyclists and other athletes.
- Promotes Fat loss
It’s very discouraging when you watch muscles that took you weeks to build get broken down. This is a site no bodybuilder wishes to see, and Ligandrol is formulated to prevent that. The supplement is an incredible anti-catabolic agent that will help you preserve and increase your lean body mass even when you are taking a calorie deficient diet. The supplement will also increase your bone cells and muscle mass which will consequently lead to a rise in metabolism promoting fat loss.
- Exclusively targets bone and muscle tissues
This is not one of those supplements that will end up affecting your prostate and other organs. When you use Ligandrol as directed, the compound will selectively target bone and muscle tissues delivering only the needed outcomes. Perhaps this is why trials are trying to investigate its benefits in older people with osteoporosis, sarcopenia, and caxechia.
- Promotes mental health
Mental health is vital to any bodybuilder out there. When you are mentally healthy gym sessions are likely to be more productive allowing you to enjoy better and faster results. Users of Ligandrol have reported how positive using the compound makes them feel and how they’ve been able to exploit this well-being positively.
- Prevents muscle wasting
Muscle wasting has been a notorious problem, especially among cancer patients. The initial studies of this compound showed promising results on its ability to preserve lean muscle mass and that why Vikings Pharmaceuticals are studying how well it can prevent muscle wasting and how to best use it for this purpose.
- Could be beneficial to hip fracture patients
The older population is the most affected by hip fractures. Lean muscle mass in this populace is much lower which makes healing of such fractures a problem. LGD’s ability to improve lean muscle mass and bone mineral density make it an ideal treatment alternative to hip fractures.
Liggandrol Side Effects?
The topic of side effects is a very subjective matter because different bodies react differently. A few minor side effects have been reported online by Ligandrol users, but not all of them can conclusively be attributed to the use of this supplement. Some are merely due to one’s intolerance or using it along with other supplements. A few of effects reported include:
- A headache
- Muscle pumps
Using Ligandrol at the right levels where your body can handle the doses will eliminate the chances of getting these side effects. Also, none of these effects are ever permanent. Any adverse effects witnessed will disappear the moment you stop using the supplement.
LGD 4033 and Testosterone Levels
One side effect that raised eyebrows is how using Ligandrol resulted in suppression of both hormone-binding globulin and total testosterone. This side effect was also identified in the first phase of clinical trials. The study, however, explained that a mini post cycle therapy helped to return the hormone’s level to baseline.
Most people have seen Ligandrol results with just 3-10 mg daily dosages. Users can expect to notice benefits after only two weeks, and these will get even better as you continue using the supplement. After three months tolerance to the drug may rise which could affect the results, and that’s another reason why PCT is recommended.
For men, 10 mg daily is the maximum dosage that you should never cross. Women, on the other hand, should never exceed 5mg daily. Female users should also know that excessive usage of Ligandrol can result in masculine effects and that’s why they should not overdose it.
How to use Ligandrol
- Bulking – You should use Ligandrol with a protein-rich diet if you are using it for bulking.
- Cutting – Use 3-5 mg of LGD 4033 daily for eight weeks if you want to add lean body mass while reducing body fat. Using it in a triple pack with S-4 and GW-501516 makes it even more useful for cutting.
- Recomping – Use Ligandrol with cardarine and GW-501516 for excellent recomp results. The dosage here should be 5-8 mg daily for eight weeks.
Post Cycle Therapy
It’s always advisable to undergo post cycle therapy when using SARMs like LGD 4033 which affect other hormones like testosterone. This allows your body to get its hormone levels back to norm while also helping to prevent fat accumulation, preserve muscle gains and maintain a good mood.
PCT duration varies from one supplement to another, but most compounds will typically require the same time as the supplementation period.
Where can I buy LGD 4033?
LGD is readily available for research purposes in various online shops, but the biggest challenge is purity and quality. With that in mind, the most recommended store to get it according to Reddit and expert reviews is from Innovative Research Compounds.
The only serious concern with LGD 4033 is its effects on testosterone levels. The good news, fortunately, is that the PCT period should help to restore testosterone levels back to normal. Other than that Ligandrol is nothing short of an outstanding SARM that’s assisting bodybuilders to enjoy a myriad of benefits. Muscles, Fat loss, stamina, strength, bone density will all receive a significant boost which should become noticeable after just two weeks.
- Increases muscle size
- Increases muscle strength
- Enhances fat burning
- Increases Testosterone
- Promotes energy
- No negative side effects
Jonathan Deventer is a passionate Certified Personal Trainer who got his Master’s Degree in Human Kinetics at the Boise State University.
He specializes in steroids, peptides, SARMS and pre-workout supplements.
- BCAK Certified Exercise Physiologist
- Certified Fitness Consultant
- Athletic Taping Level I & II BCRPA
- Personal Trainer, BCRPA
- Supervisor of Fitness Leaders